- Launched in 2007
- Indexed in MEDLINE, Scopus and Directory of Open Access Journals (DOAJ)
- Listed in PubMed and freely available via PubMed Central
- All articles are made freely available online immediately upon publication
- Rigorous peer review and rapid publication
- Free to publish (no article fees)
The journal is a member of the Committee on Publication Ethics (COPE).Submission information
Please direct any queries to email@example.com.
This journal changed its publication mode from subscription to open access in 2019.
Therapeutic Advances in Cardiovascular Disease delivers the highest quality peer-reviewed open access original research articles, reviews, and scholarly comment on pioneering efforts and innovative studies in the medical treatment of cardiac and circulatory conditions. The journal has a strong clinical and pharmacological focus and is aimed at an international audience of clinicians and researchers in cardiology, circulatory disorders and related disciplines, providing an online forum for rapid dissemination of recent research and perspectives in this area.
The editors welcome original research articles across all areas of cardiology.
The journal publishes original research articles and review articles primarily. Original research manuscripts may include laboratory, animal or human/clinical studies - all phases. Letters to the Editor and Case Reports will also be considered.
Review articles include expert opinion/perspective reviews (including single-drug and drug class reviews), narrative reviews and therapeutic area reviews. Systematic reviews, meta-analyses, postmarketing and health economic and pharmacoeconomic reviews are also welcomed. The appropriate EQUATOR Network reporting guidelines should be follows (e.g. CONSORT for randomized, controlled trials and PRISMA for systematic reviews/meta-analyses). The journal endorses the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of the first patient enrolment. However, consistent with the AllTrials campaign, retrospectively registered trials will be considered if the justification for late registration is acceptable.
The journal adheres to a blind review process in which the reviewer's name is routinely withheld from the author unless the reviewer requests a preference for their identity to be revelaed. Manuscripts are reviewed by at least two referees; a first editorial decision is generally reached within 3 weeks of submission and Online First publication is usually within 3 weeks of Acceptance.
|Luis Alcocer MD||Hospital General of Mexico, Mexico City, Mexico|
|Gjumrakch Aliev PhD, MD||University of Atlanta, USA|
|Fabio Angeli MD||Clinical Research Unit, 'S.M. della Misericordia' Hospital, Perugia, Italy|
|William Arendshorst PhD||University of North Carolina, Chapel Hill, North Carolina, USA|
|David B. Averill PhD||Geisinger Commonwealth School of Medicine, Pennsylvania, USA|
|Mario Bendersky PhD||University of Córdoba, Córdoba, Argentina|
|Josephine P. Briggs MD||National Center for Complementary and Integrative Health (NCCIH), Maryland, USA|
|Victoria M. Cachofeiro MD||Universidad Complutense, Madrid, Spain|
|Vito Campese MD||University of Southern California, Los Angeles, California, USA|
|Jose Cangiano MD||San Juan Bautista, San Juan, Puerto Rico|
|Robert Carey MD||University of Virginia School of Medicine, Charlottesville, Virginia, USA|
|Larisa Cavallari||University of Florida, Gainesville, FL, USA|
|Angel Chamorro MD||University of Barcelona, Barcelona, Spain|
|Thomas M. Coffman MD||Duke University Medical Center, Durham, North Carolina, USA|
|Paul Conlin MD||Brigham and Women's Hospital, Boston, Massachusetts, USA|
|Kevin P Davy MD||Virginia Polytechnic Institute and State University, Virginia, USA|
|Walmor De Mello MD||University of Puerto Rico, San Juan, Puerto Rico, USA|
|Javier Diez MD||University of Navarra, Pamplona, Spain|
|Brent Egan MD||Medical University of South Carolina, South Carolina, Charleston, USA|
|Fernando Elijovich MD||Texas A&M Health Science Center , College of Medicine, Texas, USA|
|Bonita Falkner MD||Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA|
|Gregory Fink MD||Michigan State University, East Lansing, Michigan, USA|
|John M Flack MD||Southern Illinois University, Illinois, USA|
|John Floras MD||University of Toronto, Toronto, Ontario, Canada|
|Toshiro Fujita MD||The University of Tokyo, Tokyo, Japan|
|Randolph L Geary MD||Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA|
|Augustus O Grant MD||Duke University Medical Center, Durham, North Carolina, USA|
|J R Haywood MD||Michigan State University, East Lansing, Michigan, USA|
|Mark C Houston MD||Hypertension Institute, St. Thomas West Hospital, Nashville, TN, USA|
|Jens Jordan MD||Institute for Clinical Pharmacology, Hannover, Germany|
|Pedro Jose MD||Georgetown University Medical Center, Washington D.C., USA|
|Luis Juncos MD||National University of Cordoba, Cordoba, Argentina|
|Jose E. Krieger MD||University of Sco Paulo Medical School, Sco Paulo, Brazil|
|Frans Leenen PhD, MD||University of Ottawa Heart Institute, Ottawa, Ontario, Canada|
|John Lekakis PhD, MD||Attikon University Hospital, Athens, Greece|
|Pavel J Levy MD||Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA|
|Giuseppe Mancia MD, PhD||University of Milan - Bicocca, Monza, Italy|
|Jawahar L Mehta MD, PhD||University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA|
|Mohan Raizada MD, PhD||University of Florida, Florida, USA|
|Josep Redon MD, PhD||Hospital Clinico Universitario, Universidad de Valencia, Valencia, Spain|
|Martin Rosas-Peralta MD, PhD||National Institute of Cardiology and Ministry of Health, City, Mexico|
|Luis Ruilope MD, PhD||Hospital 12 de Octubre, Madrid, Spain|
|Kathryn Sandberg PhD||Georgetown University, Washington D.C., USA|
|James R Sowers MD||University of Missouri-Columbia School of Medicine, Columbia, MO, USA|
|Rhian M. Touyz MBBCh, MSc, PhD||University of Glasgow, Glasgow, Scotland, UK|
|Jasmina Varagic MD, PhD||Wake Forest University School of Medicine, Winston-Salem, NC, USA|
|George Vauquelin MD, PHD||Vrije Universiteit Brussels, Brussels, Belgium|
|Massimo Volpe MD||Ospedale Sant'Andrea, Univerisity "La Sapienza" Rome, Italy|
|R Clinton Webb PhD, MS||Medical College of Georgia, Augusta, Georgia, USA|
|Matthew R. Weir MD||University of Maryland School of Medicine, Baltimore, Maryland, USA|
|Bryan Williams MD||University of Leicester, Leicester, UK|
|Yoram Yagil PhD, MD||Ben-Gurion University, Ashkelon, Israel|
|Irving Zucker PhD, MD||University of Nebraska Medical Center, Omaha, Nebraska, USA|
This Journal is a member of the Committee on Publication Ethics.
This Journal recommends that authors follow the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).
All articles are listed on PubMed.
Please read the guidelines below then visit the Journal’s submission site http://mc.manuscriptcentral.com/tac to upload your manuscript. Please note that manuscripts not conforming to these guidelines may be returned. Remember you can log in to the submission site at any time to check on the progress of your paper through the peer review process.
Only manuscripts of sufficient quality that meet the aims and scope of Therapeutic Advances in Cardiovascular Disease will be reviewed.
As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you.
Therapeutic Advances in Cardiovascular Disease may accept submissions of papers that have been posted on pre-print servers; please alert the Editorial Office when submitting (contact details are at the end of these guidelines) and include the DOI for the preprint in the designated field in the manuscript submission system. Authors should not post an updated version of their paper on the preprint server while it is being peer reviewed for possible publication in the journal. If the article is accepted for publication, the author may re-use their work according to the journal's author archiving policy.
If your paper is accepted, you must include a link on your preprint to the final version of your paper.
- Open Access
- Article Processing Charge (APC)
- Article types
- Editorial policies
4.1 Peer review policy
4.5 Declaration of conflicting interests
4.6 Research ethics and patient consent
4.7 Clinical trials
4.8 Reporting guidelines
- Publishing policies
5.1 Publication ethics
5.2 Contributor's publishing agreement
- Preparing your manuscript
6.2 Artwork, figures and other graphics
6.3 Supplementary material
6.4 Reference style
6.5 English language editing services
- Submitting your manuscript
7.2 Information required for completing your submission
- On acceptance and publication
8.1 SAGE Production
8.2 Online First publication
8.3 Access to your published article
8.4 Promoting your article
- Further information
Therapeutic Advances in Cardiovascular Disease is an open access, peer-reviewed journal. Each article accepted by peer review is made freely available online immediately upon publication, is published under a Creative Commons license and will be hosted online in perpetuity. Publication costs of the journal are covered by the collection of article processing charges which are paid by the funder, institution or author of each manuscript upon acceptance. There is no charge for submitting a paper to the journal.
The article processing charge (APC) for this journal is currently 1500 USD, discounted from the full rate of 2000 USD.
3. Article Types
Therapeutic Advances in Cardiovascular Disease considers the following article types for publication:
Original Articles. The Editors will consider preclinical, interventional and observational studies with clearly stated aims, well-reported methodology (including main outcome measures) and results, and a discussion of the results in the context of the published literature.
Review Articles. These manuscripts are usually commissioned by the Editors, but the following types of high-quality review will be considered:
(a) General reviews that provide a synthesis of an area that fits within the aims and scope of the journal;
(b) Perspective reviews – review articles that address important new areas of general interest and afford the author the opportunity to present a forward-looking perspective on the topic;
(c) Drug reviews – review articles focusing on the available evidence for the use of a particular drug or combination therapy.
Systematic Reviews – these should answer a specific research question and be reported according to the PRISMA guidelines. They should also include a PRISMA flow chart as a cited figure and a completed PRISMA checklist as a supplementary file (please see section 2.8).
Meta-analyses – these should answer a specific research question and be reported according to the PRISMA guidelines. They should also include a PRISMA flow chart as a cited figure and a completed PRISMA checklist as a supplementary file (please see section 2.8).
Case Series – these descriptive structured reports (which do not involve formal hypotheses or pre-specified methodology or analyses) of a small group of patients should include a full review of the pertinent literature and a section on implications for clinical care.
Study Protocols – these can be for forthcoming or ongoing research. Information on trial registration (where applicable) and ethics approval should be included in the manuscript.
Letters to the Editor – these brief opinion pieces should be as concise as possible, usually no more than 1000 words.
The journal considers the results of rigorous, well-designed studies that demonstrate “no effect” or that fail to replicate previous work (“negative data”) as important to the advancement of science. Therapeutic Advances in Cardiovascular Disease welcomes short reports on null or negative results as long as the papers are based on strong hypothesis testing.
The journal's policy is to obtain at least two independent reviews of each article. Therapeutic Advances in Cardiovascular Disease operates a conventional single-blind reviewing policy in which the reviewer's name is always concealed from the submitting author. Referees will be encouraged to provide substantive, constructive reviews that provide suggestions for improving the work and distinguish between mandatory and non-mandatory recommendations. All manuscripts accepted for publication are subject to editing for presentation, style and grammar. Any major redrafting is agreed with the author but the Editor's decision on the text is final.
As part of the submission process you will be asked to provide the names of 3 peers who could be called upon to review your manuscript. Recommended reviewers should be experts in their fields and should be able to provide an objective assessment of the manuscript. Please be aware of any conflicts of interest when recommending reviewers. Examples of conflicts of interest include (but are not limited to) the below:
- The reviewer should have no prior knowledge of your submission
- The reviewer should not have recently collaborated with any of the authors
- Reviewer nominees from the same institution as any of the authors are not permitted
Please note that the Editors are not obliged to invite/reject any recommended/opposed reviewers to assess your manuscript.
The Editor or members of the Editorial Board may occasionally submit their own manuscripts for possible publication in the journal. In these cases, the peer review process will be managed by alternative members of the Board and the submitting Editor/Board member will have no involvement in the decision-making process.
Papers should only be submitted for consideration once consent is given by all contributing authors. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.
The list of authors should include all those who can legitimately claim authorship. This is all those who:
- Made a substantial contribution to the concept or design of the work; or acquisition, analysis or interpretation of data,
- Drafted the article or revised it critically for important intellectual content,
- Approved the version to be published,
- Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content.
Authors should meet the conditions of all of the points above. When a large, multicentre group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship.
Acquisition of funding, collection of data, or general supervision of the research group alone does not constitute authorship, although all contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section. Please refer to the International Committee of Medical Journal Editors (ICMJE) authorship guidelines for more information on authorship.
All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support.
Any acknowledgements should appear first at the end of your article prior to your Declaration of Conflicting Interests (if applicable), any notes and your References.
Individuals who provided writing assistance, e.g. from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance. It is not necessary to disclose use of language polishing services.
Therapeutic Advances in Cardiovascular Disease requires all authors to acknowledge their funding in a consistent fashion under a separate heading. Please visit the Funding Acknowledgements page on the SAGE Journal Author Gateway to confirm the format of the acknowledgment text in the event of funding, or state that: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.
It is the policy of Therapeutic Advances in Cardiovascular Disease to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles.
Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of your manuscript, after any acknowledgements and prior to the references. If no conflict exists, please state that ‘The Author(s) declare(s) that there is no conflict of interest’. For guidance on conflict of interest statements, please see the ICMJE recommendations here.
4.6 Research ethics and patient consent
Medical research involving human subjects must be conducted according to the World Medical Association Declaration of Helsinki.
Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, and all papers reporting animal and/or human studies must state in the methods section that the relevant Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure that you have provided the full name and institution of the review committee, in addition to the approval number.
For research articles, authors are also required to state in the methods section whether participants provided informed consent and whether the consent was written or verbal.
Information on informed consent to report individual cases or case series should be included in the manuscript text. A statement is required regarding whether written informed consent for patient information and images to be published was provided by the patient(s) or a legally authorized representative. Please do not submit the patient’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The Journal requests that you confirm to us, in writing, that you have obtained written informed consent but the written consent itself should be held by the authors/investigators themselves, for example in a patient’s hospital record. The confirmatory letter may be uploaded with your submission as a separate file.
Please also refer to the ICMJE Recommendations for the Protection of Research Participants.
All research involving animals submitted for publication must be approved by an ethics committee with oversight of the facility in which the studies were conducted. The journal has adopted the Consensus Author Guidelines on Animal Ethics and Welfare for Veterinary Journals published by the International Association of Veterinary Editors.
4.7 Clinical trials
Therapeutic Advances in Cardiovascular Disease conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first patient enrolment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.
4.8 Reporting guidelines
The relevant EQUATOR Network reporting guidelines should be followed depending on the type of study. For example, all randomized controlled trials submitted for publication should include a completed CONSORT flow chart as a cited figure and the completed CONSORT checklist should be uploaded with your submission as a supplementary file. Systematic reviews and meta-analyses should include the completed PRISMA flow chart as a cited figure and the completed PRISMA checklist should be uploaded with your submission as a supplementary file. The EQUATOR wizard can help you identify the appropriate guideline.
Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.
Therapeutic Advances in Cardiovascular Disease encourages all authors submitting any primary data used in their research articles alongside their article submissions to be published in the online version of the journal, or provide detailed information in their articles on how the data can be obtained. This information should include links to third-party data repositories or detailed contact information for third-party data sources. Data available only on an author-maintained website will need to be loaded onto either the journal’s platform or a third-party platform to ensure continuing accessibility. Examples of data types include but are not limited to statistical data files, replication code, text files, audio files, images, videos, appendices, and additional charts and graphs necessary to understand the original research. The editor may consider limited embargoes on proprietary data. The editor can also grant exceptions for data that cannot legally or ethically be released. All data submitted should comply with Institutional or Ethical Review Board requirements and applicable government regulations. For further information, please contact the editorial office at firstname.lastname@example.org
5. Publishing Policies
5.1 Publication ethics
SAGE is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the SAGE Author Gateway.
Therapeutic Advances in Cardiovascular Disease and SAGE take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of published articles. Equally, we seek to protect the reputation of the journal against malpractice. Submitted articles may be checked with duplication-checking software. Where an article, for example, is found to have plagiarised other work or included third-party copyright material without permission or with insufficient acknowledgement, or where the authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article; taking up the matter with the head of department or dean of the author's institution and/or relevant academic bodies or societies; or taking appropriate legal action.
5.1.2 Prior publication
If material has been previously published it is not generally acceptable for publication in a SAGE journal. However, there are certain circumstances where previously published material can be considered for publication. Please refer to the guidance on the SAGE Author Gateway or if in doubt, contact the Editor at the address given below.
Before publication, SAGE requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. Therapeutic Advances in Cardiovascular Disease publishes manuscripts under Creative Commons licenses. The standard license for the journal is Creative Commons by Attribution Non-Commercial (CC BY-NC), which allows others to re-use the work without permission as long as the work is properly referenced and the use is non-commercial. For more information, you are advised to visit SAGE's OA licenses page.
Alternative license arrangements are available, for example to meet particular funder mandates, made at the author’s request.
6. Preparing your manuscript for submission
The preferred format for your manuscript is Word. Word templates are available on the Manuscript Submission Guidelines page of our Author Gateway.
For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit SAGE’s Manuscript Submission Guidelines.
6.3 Supplementary material
This journal is able to host additional materials online (e.g. datasets, podcasts, videos, images etc) alongside the full-text of the article. For more information please refer to our guidelines on submitting supplementary files.
6.4 Reference style
Therapeutic Advances in Cardiovascular Disease adheres to the SAGE Vancouver reference style. View the SAGE Vancouver guidelines to ensure your manuscript conforms to this reference style.
6.5 English language editing services
Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using SAGE Language Services. Visit SAGE Language Services on our Journal Author Gateway for further information.
7. Submitting your manuscript
Therapeutic Advances in Cardiovascular Disease is hosted on SAGE Track, a web based online submission and peer review system powered by ScholarOne™ Manuscripts. Visit http://mc.manuscriptcentral.com/tac to login and submit your article online.
IMPORTANT: Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the journal in the past year it is likely that you will have had an account created. For further guidance on submitting your manuscript online please visit ScholarOne Online Help.
As part of our commitment to ensuring an ethical, transparent and fair peer review process SAGE is a supporting member of ORCID, the Open Researcher and Contributor ID. ORCID provides a unique and persistent digital identifier that distinguishes researchers from every other researcher, even those who share the same name, and, through integration in key research workflows such as manuscript and grant submission, supports automated linkages between researchers and their professional activities, ensuring that their work is recognized.
The collection of ORCID IDs from corresponding authors is now part of the submission process of this journal. If you already have an ORCID iD you will be asked to associate that to your submission during the online submission process. We also strongly encourage all co-authors to link their ORCID ID to their accounts in our online peer review platforms. It takes seconds to do: click the link when prompted, sign into your ORCID account and our systems are automatically updated. Your ORCID iD will become part of your accepted publication’s metadata, making your work attributable to you and only you. Your ORCID iD is published with your article so that fellow researchers reading your work can link to your ORCID profile and from there link to your other publications.
7.2 Information required for completing your submission
You will be asked to provide contact details and academic affiliations for all co-authors via the submission system and identify who is to be the corresponding author. These details must match what appears on your manuscript. At this stage please ensure you have included all the required statements and declarations and uploaded any additional supplementary files (including reporting guidelines where relevant).
Please also ensure that you have obtained any necessary permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please see the Copyright and Permissions page on the SAGE Author Gateway.
8. On acceptance and publication
Your SAGE Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will made available to the corresponding author via our editing portal SAGE Edit, or by email to the corresponding author and should be returned promptly. Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate. Please note that if there are any changes to the author list at this stage all authors will be required to complete and sign a form authorising the change.
Online First allows final articles (completed and approved articles awaiting assignment to a future issue) to be published online prior to their inclusion in a journal issue, which significantly reduces the lead time between submission and publication. Visit the SAGE Journals help page for more details, including how to cite Online First articles.
SAGE provides authors with online access to their final article.
8.4 Promoting your article
Publication is not the end of the process! You can help disseminate your paper and ensure it is as widely read and cited as possible. The SAGE Author Gateway has numerous resources to help you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice. In addition, SAGE is partnered with Kudos, a free service that allows authors to explain, enrich, share, and measure the impact of their article. Find out how to maximise your article’s impact with Kudos.
9. Further information
Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the Therapeutic Advances in Cardiovascular Disease editorial office as follows:
For all commercial sales and sponsorship enquiries, including advertising, reprints and supplements, please contact:
Commercial Sales Team, London, UK Tel: +44 20 7336 1205 Email: email@example.com