You are here

International Journal of Toxicology

International Journal of Toxicology

Published in Association with American College of Toxicology
Other Titles in:
Toxicologic Pathology | Toxicology

eISSN: 1092874X | ISSN: 10915818 | Current volume: 43 | Current issue: 2 Frequency: Bi-monthly

International Journal of Toxicology (IJT) offers academic, industry, and regulatory toxicologists, as well as toxicology consultants, timely, peer-reviewed, multidisciplinary articles and incisive reviews on contemporary issues in toxicology, plus safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. Each issue of IJT provides an important forum for articles that promote basic toxicology research, as well as those that facilitate and improve toxicology practice.

We are currently seeking manuscript submissions in these (and related) areas:
• Advances in drug development
• Safety assessments
• New therapeutic targets
• Alternatives/refinement to use of animals in toxicology
• Target organ toxicology
• Immunotoxicology testing advances/challenges
• Regulatory issues
• New approaches to toxicological testing
and data interpretation
• Risk assessment advances
• Biomarkers of toxicity
• Mechanisms of toxicology

IJT also publishes invited reviews, articles based on symposia, book and media reviews, and editorials. IJT publishes sponsored supplemental issues, including three issues each year devoted to contributions from the Cosmetic Ingredient Review Expert Panel.

International Journal of Toxicology, the official journal of the American College of Toxicology (ACT), welcomes contributions from authors, reviewers, and Editorial Board members from all backgrounds, and supports aspiring and established toxicology professionals. ACT is committed to diversity, equity, and inclusion (DEI) within our organization. We strive to empower individuals to actively engage, collaborate, and exchange ideas, and we embrace diversity in expression, perspective, and experience.

International Journal of Toxicology (IJT) offers academic, industry, and regulatory toxicologists, as well as toxicology consultants, timely, peer-reviewed, multidisciplinary articles and incisive reviews on contemporary issues in toxicology, plus safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. Each issue of IJT provides an important forum for articles that promote basic toxicology research, as well as those that facilitate and improve toxicology practice.

IJT also publishes invited reviews, articles based on symposia, book and media reviews, and editorials. IJT publishes sponsored supplemental issues, including three issues each year devoted to contributions from the Cosmetic Ingredient Review Expert Panel.

Editor
Mary Beth Genter, PhD University of Cincinnati, USA
Associate Editors
Bruce K. Bernard, PhD SRA Consulting, Cambridge, MD, USA
Marion F. Ehrich, PhD VA-MD Regional College of Veterinary Medicine, Blacksburg, VA, USA
Donald G. Stump, PhD Charles River, Ashland, OH, USA
Book Review Editor
Robert W. Kapp, Jr., PhD BioTox, Stafford Township, NJ, USA
Editors Emeriti
Editorial Board
Krishna P. Allamneni, PhD Concarlo Therapeutics, Inc., Brooklyn, NY, USA
Shana Azri-Meehan, PhD Cardinal Health, Millington, NJ, USA
Theodore J. Baird, PhD Charles River, Mattawan, MI, USA
Lisa D. Beilke, PhD Toxicology Solutions, Inc., San Diego, CA, USA
Susan Borghoff, PhD ToxStrategies, Inc., Cary, NC, USA
William J. Brock, PhD Brock Scientific Consulting, Montgomery, MD
Alan P. Brown, PhD Novartis Institutes for BioMedical Research, Cambridge, MA, USA
Lorrene A. Buckley, PhD Eli Lilly and Company, Indianapolis, IN, USA
John A. Budny, PhD PharmaCal, Redding, CA, USA
Florence G. Burleson, PhD BRT-Burleson Research Technologies, Inc., Morrisville, NC, USA
Gary R. Burleson, PhD BRT-Burleson Research Technologies, Inc., Morrisville, NC, USA
Leigh Ann Burns Naas, PhD Magnolia Toxicology Consulting, LLC, Traverse City, MI, USA
Erica Carroll, DVM, PhD Covance, Greenfield, IN, USA
Charleata Carter, PhD Carter Consulting, Greensboro, NC, USA
Scott Coleman, PhD Acceleron, Attleboro, MA, USA
David Compton, PhD Annandale, NJ, USA
Mary Ellen Cosenza, MEC Regulatory & Toxicology Consulting, LLC, Moorpark, CA, USA
Matthew Z. Dieter, PhD Eli Lilly and Company, Indianapolis, IN, USA
Sandy Eldridge, PhD National Cancer Institute, NIH, Bethesda, MD, USA
Li-jie Fu, PhD Shin Nippon Biomedical Labs, Ltd, Beijing, China
Shayne C. Gad, PhD Gad Consulting Services, Cary, NC, USA
Hanan N. Ghantous, PhD US FDA, Silver Spring, MD, USA
Robin C. Guy, MS Robin Guy Consulting, LLC, Lake Forest, IL, USA
Bert Haenen, PhD Janssen Research and Development, Beerse, Belgium
Jerry F. Hardisty EPL Inc., Research Triangle Park, NC, USA
Stephen B. Harris, PhD Stephen B. Harris Group, San Diego, CA, USA
Kenneth L. Hastings, DrPH Hastings Toxicology Consulting, LLC, Mount Airy, MD, USA
Alan M. Hoberman, PhD Charles River, Horsham, PA, USA
David W. Hobson, PhD LoneStar PharmTox LLC, Boerne, TX, USA
Debie Hoivik, PhD Akebia Therapeutics, Cambridge, MA, USA
Heidi Hsieh, PhD Covance, Madison, WI, USA
Elaine V. Knight, PhD National Cancer Institute, NIH, Bethesda, MD, USA
Stephen B. Montgomery, PhD Consulting Nonclinical Safety Assessment, Alpharetta, GA, USA
P. Balakrishna Murthy, PhD, DSc Consultant Toxicologist, Chennai, India
Kenneth J. Olivier, Jr., PhD Morphic Therapeutics, Attleboro, MA, USA
Madhav Paranjpe, DVM, PhD Charles River, Mattawan, MI, USA
Charles W. Qualls, Jr., DVM, PhD Thousand Oaks, California, USA
Gunda Reddy, PhD Fallston, MD, USA
Robert Roy, PhD Northland Toxicology Consultants, LLC, MN, USA
Alan H. Stokes, PhD GSK, Rockville, MD, USA
Tao Wang, MD, PhD Coherus BioSciences, Redwood City, CA, USA
Adam Woolley, MSc, FRCPath ForthTox Ltd., Linlithgow, Scotland, UK
David Woolley, PhD Forthtox, Ltd., Linlithgow, Scotland
  • Academic Search - Premier
  • Academic Search Elite
  • Biomedical Reference Collection: Comprehensive Edition
  • Chemical Abstracts Service (CAS)
  • Chemical Safety Newsbase
  • Clarivate Analytics: BIOSIS Previews
  • Clarivate Analytics: Biological Abstracts
  • Consumer Health Complete™
  • EBSCO: Environment Index
  • EBSCO: Health Source - Nursing/Academic Edition
  • EBSCOhost: Academic Search Complete
  • EMBASE
  • EMBiology
  • Elsevier BV: BIOBASE
  • Environment Complete
  • Laboratory Hazards Bulletin
  • MEDLINE
  • ProQuest
  • RSC Publishing
  • SIIC Databases
  • SafetyLit
  • Science Citation Index Expanded (Web of Science)
  • Scopus
  • TOXLINE
  •  

    Average time from submission to first decision: 13 days

    International Journal of Toxicology (IJT) offers academic, industry, and regulatory toxicologists, as well as toxicology consultants, timely, peer-reviewed, multidisciplinary articles and incisive reviews on contemporary issues in toxicology, plus safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. Each issue of IJT provides an important forum for articles that promote basic toxicology research, as well as those that facilitate and improve toxicology practice.In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Ingredient Review Expert Panel.

    All authors are now required to complete an authorship form upon submission of their article. Any author found not to be incompliance with the Uniform Requirements for Manuscripts Submitted to Biomedical Journals formulated by the International Committee on Medical Journal Editors (ICJME) and requirements for authorship will be relisted under acknowledgements.

    This journal is a member of the Committee on Publication Ethics.

    There are no fees payable to submit or publish in this Journal. Open Access options are available - see section 3.3 below.

    Please read the guidelines below then submit your manuscripts electronically to http://mc.manuscriptcentral.com/uito. Authors will be asked to set up an online account in the SageTRACK system, powered by ScholarOne. Please note that manuscripts not conforming to these guidelines may be returned. Only manuscripts of sufficient quality that meet the aims and scopes of IJT will be reviewed. For questions regarding submission, contact Mary Beth Genter, Editor, at gentermb@ucmail.uc.edu.

    International Journal of Toxicology, the official journal of the American College of Toxicology (ACT), welcomes contributions from authors, reviewers, and Editorial Board members from all backgrounds, and supports aspiring and established toxicology professionals. ACT is committed to diversity, equity, and inclusion (DEI) within our organization. We strive to empower individuals to actively engage, collaborate, and exchange ideas, and we embrace diversity in expression, perspective, and experience.

    Sage Publishing disseminates high-quality research and engaged scholarship globally, and we are committed to diversity and inclusion in publishing. We encourage submissions from a diverse range of authors from across all countries and backgrounds.

    As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere. Please see our guidelines on prior publication and note that IJT may accept submissions of papers that have been posted on pre-print servers; please alert the Editorial Office when submitting (contact details are at the end of these guidelines) and include the DOI for the preprint in the designated field in the manuscript submission system. Authors should not post an updated version of their paper on the preprint server while it is being peer reviewed for possible publication in the journal. If the article is accepted for publication, the author may re-use their work according to the journal's author archiving policy.

    If your paper is accepted, you must include a link on your preprint to the final version of your paper.

    Manuscript Submission Guidelines

    1. What do we publish?

    1.1 Aims & Scope

    1.2 Article types

    1.3 Writing your paper

    2. Editorial policies

    2.1 Peer review policy

    2.2 Authorship

    2.3 Acknowledgements

    2.4 Funding

    2.5 Declaration of conflicting interests

    2.6 Research ethics and patient consent

    2.7 Clinical trials

    2.8 Reporting guidelines

    2.9 Data

    3. Publishing policies

    3.1 Publication ethics

    3.2 Contributor’s publishing agreement

    3.3 Open access and author archiving

    3.4 Artificial Intelligence

    4. Preparing your manuscript

    4.1 Formatting

    4.2 Artwork, figures and other graphics

    4.3 Supplemental material

    4.4 Reference style

    4.5 English language editing services

    5. Submitting your manuscript

    5.1 ORCID

    5.2 Information required for completing your submission

    5.3 Permissions

    6. On acceptance and publication

    6.1 Sage Production

    6.2 Online First publication

    6.3 Access to your published article

    6.4 Promoting your article

    7. Further information

     

    1. What do we publish?

    1.1 Aims & Scope

    Before submitting your manuscript to International Journal of Toxicology please ensure you have read the Aims & Scope.

    1.2 Article types

    International Journal of Toxicology (the Journal) is the official journal of the American College of Toxicology and is published by Sage. The Journal publishes timely, peer-reviewed original research papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Ingredient Review Expert Panel. 

    The Journal does NOT publish the following: case reports, case studies, papers dealing with chemoprotection/therapeutic interventions (i.e. the protective/therapeutic effect of agent X against the toxicity of chemical Y), papers showing results with poorly characterized natural products, or papers with an ecotoxicology focus.

    1.3 Writing your paper

    The Sage Author Gateway has some general advice and on how to get published, plus links to further resources.

    1.3.1 Make your article discoverable

    For information and guidance on how to make your article more discoverable, visit our Gateway page on How to Help Readers Find Your Article Online

    2. Editorial policies

    Guidelines for manuscripts describing natural products/natural products extracts: International Journal of Toxicology receives numerous submissions that focus on natural products or derivatives (most commonly extracts). In order to ensure the scientific reproducibility and quality of these submissions, the following parameters, at a minimum, must be addressed in the manuscript: (a) source and availability of material [including whether wild or cultivated]; (b) selection of material [in the case of plants, the plant selected for collection should be taxonomically the same as recommended by the national pharmacopeia or other related document]; (c) collection of the material; (d) processing and preparation of material; (e) storage conditions of the neat test substance and the dosing formulation; (f) analytic method(s) used to assure stability; (g) phytochemical analysis of the material, or other quantitative analytical evaluation that demonstrates the composition of the material. Include verification of stability and purity of the neat test substance under a verifiable method; (h) dose formulation analysis (e.g. quantitative measurement of homogeneity, stability and dose verification analysis of the test substance inthevehicleduringandunderthesametestconditions as the definitive study). Excellent guidance on preparation and testing of natural products, their extracts, etc. has been detailed by the World Health Organization and the Foundation for Medical Research, India.

    2.1 Peer review policy

    Manuscripts that meet the journal requirements are peer reviewed by experts from the Journal’s Editorial Board or other qualified reviewers. Reviewers are asked to return their peer reviews within three weeks. Guidelines for reviewing manuscripts are posted on the American College of Toxicology website: http://www.actox.org/journal/intlJournal.asp.

    IJT is committed to delivering high quality, fast peer-review for your paper, and as such has partnered with Publons. Publons is a third party service that seeks to track, verify and give credit for peer review. Reviewers for International Journal of Toxicology can opt in to Publons in order to claim their reviews or have them automatically verified and added to their reviewer profile. Reviewers claiming credit for their review will be associated with the relevant journal, but the article name, reviewer’s decision and the content of their review is not published on the site. For more information visit the Publons website.

    The Editor or members of the Editorial Board may occasionally submit their own manuscripts for possible publication in the journal. In these cases, the peer review process will be managed by alternative members of the Board and the submitting Editor/Board member will have no involvement in the decision-making process.

    2.2 Authorship

    Papers should only be submitted for consideration once consent is given by all contributing authors. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.

    The list of authors should include all those who can legitimately claim authorship. This is all those who:

    (i) Made a substantial contribution to the concept or design of the work; or acquisition, analysis or interpretation of data,

    (ii) Drafted the article or revised it critically for important intellectual content,

    (iii) Approved the version to be published,

    (iv) Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content.

    Authors should meet the conditions of all of the points above. When a large, multicentre group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship.

    Acquisition of funding, collection of data, or general supervision of the research group alone does not constitute authorship, although all contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section. Please refer to the International Committee of Medical Journal Editors (ICMJE) authorship guidelines for more information on authorship.

    Please note that AI chatbots, for example ChatGPT, should not be listed as authors. For more information see the policy on Use of ChatGPT and generative AI tools.

    2.3 Acknowledgements

    All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support.

    2.3.1 Third party submissions
    Where an individual who is not listed as an author submits a manuscript on behalf of the author(s), a statement must be included in the Acknowledgements section of the manuscript and in the accompanying cover letter. The statements must:

    • Disclose this type of editorial assistance – including the individual’s name, company and level of input
    • Identify any entities that paid for this assistance
    • Confirm that the listed authors have authorized the submission of their manuscript via third party and approved any statements or declarations, e.g. conflicting interests, funding, etc.

    Where appropriate, Sage reserves the right to deny consideration to manuscripts submitted by a third party rather than by the authors themselves.

    2.3.2 Writing assistance

    Individuals who provided writing assistance, e.g. from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance. It is not necessary to disclose use of language polishing services.

    2.4 Funding

    Funding: International Journal of Toxicology requires all authors to disclose their funding in a consistent fashion under a “Funding” heading. Please see the Funding Acknowledgements page on the Sage Journal Author Gateway to confirm the format for disclosing funding. If the work was performed without any specific funding, authors should state “This research received no specific grant from any funding agency in the public, commercial, private, or not-for-profit sectors”.

     

    2.5 Conflict of Interest  disclosure

    International Journal of Toxicology requires all authors to disclose any possible conflicts of interest. Sufficient disclosure may include divulging affiliation as members of industrial or governmental organizations, academic support, non-profit consulting, advocacy, and all sources of financial and material support for studies and manuscripts submitted. Please ensure that that a “Declaration of Conflicting Interest” statement is included at the end of your manuscript, after the Acknowledgements section and prior to the references. If no COI exists, please state that “The Author(s) declare(s) that there is/are not conflict(s) of interest”.

    2.6 Research ethics and patient consent

    Medical research involving human subjects must be conducted according to the World Medical Association Declaration of Helsinki

    Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, and all papers reporting animal and/or human studies must state in the methods section that the relevant Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure that you have provided the full name and institution of the review committee, in addition to the approval number.

    For research articles, authors are also required to state in the methods section whether participants provided informed consent and whether the consent was written or verbal.

    Information on informed consent to report individual cases or case series should be included in the manuscript text. A statement is required regarding whether written informed consent for patient information and images to be published was provided by the patient(s) or a legally authorized representative. Please do not submit the patient’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The Journal requests that you confirm to us, in writing, that you have obtained written informed consent but the written consent itself should be held by the authors/investigators themselves, for example in a patient’s hospital record. The confirmatory letter may be uploaded with your submission as a separate file.

    Please also refer to the ICMJE Recommendations for the Protection of Research Participants

    All research involving animals submitted for publication must be approved by an ethics committee with oversight of the facility in which the studies were conducted. The journal has adopted ARRIVE guidelines.

    Manuscripts submitted to International Journal of Toxicology should clearly state their compliance with the guidelines and principles listed therein and should indicate that animal protocols were reviewed and approved by an institutional panel. The American College of Toxicology Policy on the Use of Animals in Toxicology is published in Issue 1 each year, and copies may be requested from the Editor.

    2.7 Clinical trials

    International Journal of Toxicology conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first patient enrolment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.

    2.8 Reporting guidelines

    The relevant EQUATOR Network reporting guidelines should be followed depending on the type of study. For example, all randomized controlled trials submitted for publication should include a completed CONSORT flow chart as a cited figure and the completed CONSORT checklist should be uploaded with your submission as a supplementary file. Systematic reviews and meta-analyses should include the completed PRISMA flow chart as a cited figure and the completed PRISMA checklist should be uploaded with your submission as a supplementary file. The EQUATOR wizard can help you identify the appropriate guideline.

    Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.

     2.9. Research data

    The journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the Sage Research Data policy pages.

    Subject to appropriate ethical and legal considerations, authors are encouraged to:

    • share your research data in a relevant public data repository
    • include a data availability statement linking to your data. If it is not possible to share your data, we encourage you to consider using the statement to explain why it cannot be shared.
    • cite this data in your research

    3. Publishing Policies

    3.1 Publication ethics

    Sage is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the Sage Author Gateway.

    3.1.1 Plagiarism

    International Journal of Toxicology and Sage take issues of copyright infringement, plagiarism, or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of articles published in the journal. Equally, we seek to protect the reputation of the journal against malpractice. Submitted articles may be checked using duplication-checking software. Where an article is found to have plagiarized other work or included third-party copyright material without permission or with insufficient acknowledgement, or where authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article (removing it from the journal); taking up the matter with the head of department or dean of the author’s institution and/or relevant academic bodies or societies; banning the author from publication in the journal or all Sage journals, or appropriate legal action.

    3.1.2 Prior publication

    If material has been previously published it is not generally acceptable for publication in a Sage journal. However, there are certain circumstances where previously published material can be considered for publication. Please refer to the guidance on the Sage Author Gateway or if in doubt, contact the Editor at the address given below.

    3.2 Contributor’s publishing agreement

    Before publication, Sage requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. Sage’s Journal Contributor’s Publishing Agreement is an exclusive licence agreement which means that the author retains copyright in the work but grants Sage the sole and exclusive right and licence to publish for the full legal term of copyright. Exceptions may exist where an assignment of copyright is required or preferred by a proprietor other than Sage. In this case copyright in the work will be assigned from the author to the society. For more information please visit the Sage Author Gateway.

    3.3 Open access and author archiving

    International Journal of Toxicology offers optional open access publishing via the Sage Choice programme and Open Access agreements, where authors can publish open access either discounted or free of charge depending on the agreement with Sage. Find out if your institution is participating by visiting Open Access Agreements at Sage. For more information on Open Access publishing options at Sage please visit Sage Open Access. For information on funding body compliance, and depositing your article in repositories, please visit Sage’s Author Archiving and Re-Use Guidelines and Publishing Policies.

    Online repositories and author rights: Authors may not post the accepted version of the article (Version 2) to online repositories (including ResearchGate, Mendeley, etc.) until 12 months after publication of the article in the journal. Authors may not post the published article (Version 3) on a website or in a repository without permission from Sage. To view your full rights as an author, visit the Sage Publishing Policies on the Journal Author Gateway.

    3.4 Artificial Intelligence 

    Use of Large Language Models and generative AI tools in writing your submission

    Sage recognizes the value of large language models (LLMs) (e.g. ChatGPT) and generative AI as productivity tools that can help authors in preparing their article for submission; to generate initial ideas for a structure, for example, or when summarizing, paraphrasing, language polishing etc. However, it is important to note that all language models have limitations and are unable to replicate human creative and critical thinking. Human intervention with these tools is essential to ensure that content presented is accurate and appropriate to the reader. Sage therefore requires authors to be aware of the limitations of language models and to consider these in any use of LLMs in their submissions:

    • Objectivity: Previously published content that contains racist, sexist or other biases can be present in LLM-generated text, and minority viewpoints may not be represented. Use of LLMs has the potential to perpetuate these biases because the information is decontextualized and harder to detect.
    •  Accuracy: LLMs can ‘hallucinate’ i.e. generate false content, especially when used outside of their domain or when dealing with complex or ambiguous topics. They can generate content that is linguistically but not scientifically plausible, they can get facts wrong, and they have been shown to generate citations that don’t exist. Some LLMs are only trained on content published before a particular date and therefore present an incomplete picture.
    • Contextual understanding: LLMs cannot apply human understanding to the context of a piece of text, especially when dealing with idiomatic expressions, sarcasm, humor, or metaphorical language. This can lead to errors or misinterpretations in the generated content.
    • Training data: LLMs require a large amount of high-quality training data to achieve optimal performance. However, in some domains or languages, such data may not be readily available, limiting the usefulness of the model.

    Guidance for authors

    Authors are required to:

    1. Clearly indicate the use of language models in the manuscript, including which model was used and for what purpose. Please use the methods or acknowledgements section, as appropriate.
    2.  Verify the accuracy, validity, and appropriateness of the content and any citations generated by language models and correct any errors or inconsistencies.
    3.  Provide a list of sources used to generate content and citations, including those generated by language models. Double-check citations to ensure they are accurate, and are properly referenced.
    4.  Be conscious of the potential for plagiarism where the LLM may have reproduced substantial text from other sources. Check the original sources to be sure you are not plagiarizing someone else’s work.
    5. Acknowledge the limitations of language models in the manuscript, including the potential for bias, errors, and gaps in knowledge.
    6.  Please note that AI bots such as ChatGPT should not be listed as an author on your submission.

    4. Preparing your manuscript for submission

     4.1 Formatting

    Preferred formats for the text and tables of your manuscript are Word DOC, RTF, XLS. LaTeX files are also accepted. The text should be double-spaced throughout and with a minimum of 3cm for left and right hand margins and 5cm at head and foot. Text should be standard 10 or 12 point. Word and (La)Tex templates are available on the Manuscript Submission Guidelines page of our Author Gateway.

     

    4.2 Artwork, figures and other graphics

     For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit Sage’s Manuscript Submission Guidelines. Figures will be uploaded as individual files and should meet the following criteria: 

        300 dpi or higher in resolution 
        .jpg or .tif files

    Figures supplied in color will appear in color online regardless of whether or not these illustrations are reproduced in color in the printed version. For specifically requested color reproduction in print, you will receive information regarding the costs from Sage after receipt of your accepted article.

     

    4.3 Supplemental material

    This Journal is able to host additional materials online (e.g. datasets, podcasts, videos, images etc) with the full-text of the article. These will be subjected to peer-review alongside the article. For more information please refer to our guidelines on submitting supplementary files, which can be found within our Manuscript Submission Guidelines page.

     

    4.4 Reference style

    International Journal of Toxicology adheres to the AMA Manual of Style. View the guide here to ensure your manuscript conforms to this style.

    References must be numbered sequentially in the text, and listed in numerical order at the end of the text.
    Typical entry for a journal article:
        Brock WJ, Woolley AP, Sugimoto T. Certification in toxicology: an international perspective of risk:benefit. Int J 
        Toxicol. 2009;28(3):147-50.

    Typical entry for journal article with >6 authors (list first 3, then et al.):

        Politano VT, Lewis EM, Hoberman AM, et al. Evaluation of the developmental toxicity of methyl 
        dihydrojasmonate (MJD) in rats. Int J Toxicol. 2008;27(3):295-299.

    Entry for book chapter:

        Baker H, Genter MB. The olfactory system and nasal mucosa as portals of entry of viruses, drugs, and other 
        exogenous agents into the brain. In: Doty RL, ed. Handbook of Olfaction and Gustation. 2nd ed. New York, NY: 
        Marcel Dekker, Inc; 2003:549.

    If you use EndNote to manage references, you can download the Sage Harvard EndNote output file [OR] the Sage Vancouver EndNote output file.

    4.5 English language editing services

    Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using Sage Language Services. Visit Sage Language Services on our Journal Author Gateway for further information.

    5. Submitting your manuscript

    Manuscripts should be submitted electronically to http://mc.manuscriptcentral.com/uito. Authors will be asked to set up an online account in the SageTRACK system, powered by ScholarOne. For questions regarding submission, contact Mary Beth Genter, Editor-in-Chief at gentermb@ucmail.uc.edu. Hard copy submissions or submissions via email to the Editor will not be acknowledged or reviewed.

    IMPORTANT: Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the Journal in the past, it is likely that you have previously created an account. For further guidance on submitting your manuscript online please visit ScholarOne Online Help.

    The following will be requested during online submission: (a) names, credentials, and complete contact information for the corresponding author; names, credentials, positions, and email addresses for all co-authors; (b) cover letter to the Editor stating explicitly that the manuscript is not under consideration by another journal; (c) abstract of 250 words or less; (d) key words; (e) abbreviations; and (f) one complete, doublespaced Microsoft Word file of the article with the following components listed in order of appearance:

    Abstract
    Main body of the article
        Introduction
        Materials and Methods
        Results
        Discussion
    Acknowledgements, including source(s) of funding
    Conflict(s) of interest
    Figure legends
    References
    Tables

    Manuscripts will not be reviewed until all necessary information has been submitted. Articles needing extensive improvements in the English presentation will be returned to the Authors for revision. Articles not in the scope of the Journal will be rejected without review. The Editor reserves the right to request original data (including histology slides) for review.

    Title, keywords and abstracts: Please supply a title, short title, an abstract and keywords to accompany your article. The title, keywords and abstract are key to ensuring that readers find your article online through online search engines such as Google or PubMed. Please refer to the information and guidance on how best to title your article by reading this blog:

    https://perspectivesblog.sagepub.com/blog/author-services/tips-for-an-effective-journal-article-title

    Translations: International Journal of Toxicology accepts abstracts translated into other languages, including Chinese. Authors seeking assistance with translation from English to Chinese, Portuguese, or Spanish should consider using Sage Language Services for a fee. Translations are performed by academics with experience in your field and includes quality control from a bilingual language expert. They will ensure that the style of the translation is in accordance with the conventions of the field and that scientific and technical terms are translated accurately. Visit Sage Language Services on our Journal Author Gateway for further information.

    5.1 ORCID

    As part of our commitment to ensuring an ethical, transparent and fair peer review process Sage is a supporting member of ORCID, the Open Researcher and Contributor ID. ORCID provides a unique and persistent digital identifier that distinguishes researchers from every other researcher, even those who share the same name, and, through integration in key research workflows such as manuscript and grant submission, supports automated linkages between researchers and their professional activities, ensuring that their work is recognized

    The collection of ORCID IDs from corresponding authors is now part of the submission process of this journal. If you already have an ORCID ID you will be asked to associate that to your submission during the online submission process. We also strongly encourage all co-authors to link their ORCID ID to their accounts in our online peer review platforms. It takes seconds to do: click the link when prompted, sign into your ORCID account and our systems are automatically updated. Your ORCID ID will become part of your accepted publication’s metadata, making your work attributable to you and only you. Your ORCID ID is published with your article so that fellow researchers reading your work can link to your ORCID profile and from there link to your other publications.

    If you do not already have an ORCID ID please follow this link to create one or visit our ORCID homepage to learn more.

    5.2 Information required for completing your submission

    You will be asked to provide contact details and academic affiliations for all co-authors via the submission system and identify who is to be the corresponding author. These details must match what appears on your manuscript. The affiliation listed in the manuscript should be the institution where the research was conducted. If an author has moved to a new institution since completing the research, the new affiliation can be included in a manuscript note at the end of the paper. At this stage please ensure you have included all the required statements and declarations and uploaded any additional supplementary files (including reporting guidelines where relevant).

    5.3 Permissions

    Please also ensure that you have obtained any necessary permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please see the Copyright and Permissions page on the Sage Author Gateway.

    6. On acceptance and publication

    6.1 Sage Production

    Your Sage Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will be made available to the corresponding author via our editing portal Sage Edit or by email, and corrections should be made directly or notified to us promptly. Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate. 

    6.2 Online First publication

    Online First allows final articles (completed and approved articles awaiting assignment to a future issue) to be published online prior to their inclusion in a journal issue, which significantly reduces the lead time between submission and publication. Visit the Sage Journals help page for more details, including how to cite Online First articles.

    6.3 Access to your published article

    Sage provides authors with online access to their final article.

    6.4 Promoting your article

    Publication is not the end of the process! You can help disseminate your paper and ensure it is as widely read and cited as possible. The Sage Author Gateway has numerous resources to help you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice.

    Where can authors post their manuscripts? Sage has adopted RoMEO Green compliant author archiving policy. The following applies under this new policy:

    · You retain copyright in your work

    · You may do whatever you wish with the version of the article you submitted to the journal (version 1).

    · Once the article has been accepted for publication, you may post the accepted version (version 2) of the article on your own personal website, your department’s website or the repository of your institution without any restrictions.

    · You may not post the accepted version (version 2) of the article in any repository other than those listed above (i.e. you may not deposit in the repository of another institution or a subject repository) until 12 months after publication of the article in the journal.

    · You may use the published article (version 3) for your own teaching needs or to supply on an individual basis to research colleagues, provided that such supply is not for commercial purposes.

    · You may use the published article (version 3) in a book you write or edit any time after publication in the journal.

    · You may not post the published article (version 3) on a website or in a repository without permission from Sage.

    · When posting or re-using the article please provide a link to the appropriate DOI for the published version of the article on Sage Journals (http://online.sagepub.com)

    7. Further information

    Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the IJT editorial office as follows:

    Mary Beth Genter, Editor, at gentermb@ucmail.uc.edu.

    7.1 Appealing the publication decision

    Editors have very broad discretion in determining whether an article is an appropriate fit for their journal. Many manuscripts are declined with a very general statement of the rejection decision. These decisions are not eligible for formal appeal unless the author believes the decision to reject the manuscript was based on an error in the review of the article, in which case the author may appeal the decision by providing the Editor with a detailed written description of the error they believe occurred.

    If an author believes the decision regarding their manuscript was affected by a publication ethics breach, the author may contact the publisher with a detailed written description of their concern, and information supporting the concern, at publication_ethics@sagepub.com

     

     

     

    Individual Subscription - Print Only

    Institutional Subscription - E-access

    Institutional Subscription & Backfile Lease - E-access Plus Backfile (All Online Content)

    Institutional Subscription - Print Only

    Institutional Print subscription inclusive of free online access

    Institutional Subscription & Backfile Lease - Combined Plus Backfile (Current Volume Print & All Online Content)

    Institutional Backfile Purchase - E-access (Content through 1998)

    Individual - Single Print Issue

    Institutional - Single Print Issue

    Subscription Information

     

    To subscribe to this journal or to purchase single/back issues, please contact Customer Service - Journals: customerservicejournals@sagepub.in  +91 (11) 4063 9222 extn 406


    To purchase bundled content, backfiles or any other electronic products, please contact: journalsales@sagepub.in


    For exciting offers and deals, write to: jmarketing@sagepub.in